BDBM50007397 1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine::CHEMBL112037

SMILES C(CN1CCN(CC1)c1ccccc1)Cc1ccc2ccccc2c1

InChI Key InChIKey=ZDMWBBFQNAAKPP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007397   

TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataKi:  4nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataIC50: 160nMAssay Description:Compound was tested for its binding affinity towards dopamine receptor D2 by using [3H]domperidone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(CHEMBL112037 | 1-(3-Naphthalen-2-yl-propyl)-4-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]MK-801 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed