BDBM50007551 3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine::CHEMBL45491::Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro-5'H-dibenzo[a,d]cycloheptene)]-4-yl(dimethyl)amine

SMILES CN(C)C1CCC2(C=C1)c1ccccc1CCc1ccc(Cl)cc21

InChI Key InChIKey=QPNVVIACYJVUOX-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50007551   

TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  2nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  2nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  94nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  94nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  550nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  550nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed