BDBM50007800 CHEMBL3233831

SMILES [H][C@@]12Cc3nc4cc(Cl)ccc4c(NCCCCCCCCCNC(=O)c4cc(O)c5C(=O)c6c(O)cccc6C(=O)c5c4)c3[C@@]([H])(CC(C)=C1)C2

InChI Key InChIKey=VZYCFKMNVCPCHV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007800   

TargetAcetylcholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50007800(CHEMBL3233831)
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50007800(CHEMBL3233831)
Affinity DataIC50: 265nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50007800(CHEMBL3233831)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant BACE1 using methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl as substrate preincubated for 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed