BDBM50008175 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(3-chloro-benzoylamino)-butyric acid::CHEMBL421438

SMILES OC(=O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NN1CCC2(CCCC2)CC1

InChI Key InChIKey=KAQJBAYMYGDBBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008175   

TargetCholecystokinin receptor type A(Rat)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008175(CHEMBL421438 | 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoy...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of [125I](BH)-CCK-8 binding to cholecystokinin type A receptor in rat pancreatic acini; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008175(CHEMBL421438 | 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoy...)
Affinity DataIC50: 1.20E+3nMAssay Description:Concentration required to inhibit by 50% the specific binding of [125I](BH)-CCK-8 to CCK-B(B2) in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008175(CHEMBL421438 | 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoy...)
Affinity DataIC50: 800nMAssay Description:Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to CCK-B in rabbit gastric glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed