BDBM50008180 4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphthalene-2-carbonyl)-amino]-butyric acid::CHEMBL125925

SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1

InChI Key InChIKey=RCDATCVHPIFQKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008180   

TargetGastrin/cholecystokinin type B receptor(Human)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008180(CHEMBL125925 | 4-(3-Aza-spiro[5.5]undec-3-ylcarbam...)
Affinity DataIC50: 2.30E+4nMAssay Description:Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to CCK-B in rabbit gastric glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008180(CHEMBL125925 | 4-(3-Aza-spiro[5.5]undec-3-ylcarbam...)
Affinity DataIC50: 600nMAssay Description:Inhibition of [125I](BH)-CCK-8 binding to cholecystokinin type A receptor in rat pancreatic acini; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Rotta Research Laboratorium

Curated by ChEMBL
LigandPNGBDBM50008180(CHEMBL125925 | 4-(3-Aza-spiro[5.5]undec-3-ylcarbam...)
Affinity DataIC50: 200nMAssay Description:Concentration required to inhibit by 50% the specific binding of [125I](BH)-CCK-8 to CCK-B(B2) in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed