BDBM50008334 CHEMBL3235169

SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(F)cc1)\C=C\C(=O)C(F)(F)F

InChI Key InChIKey=AOTXFCOLABDNJL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50008334   

TargetCarbonic anhydrase 9(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50008334(CHEMBL3235169)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50008334(CHEMBL3235169)
Affinity DataKi:  29nMAssay Description:Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50008334(CHEMBL3235169)
Affinity DataKi:  419nMAssay Description:Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50008334(CHEMBL3235169)
Affinity DataKi:  433nMAssay Description:Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed