BDBM50008704 CHEMBL3235972

SMILES Fc1ccc(NC(=O)N2CC(F)(F)c3ccccc3C2c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=UIHWUXUEBNUTFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008704   

LigandPNGBDBM50008704(CHEMBL3235972)
Affinity DataIC50: 324nMAssay Description:Antagonist activity at human TRPM8 assessed as inhibition of icilin-induced Ca2+ influx incubated 2.5 mins prior to icilin challenge by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
LigandPNGBDBM50008704(CHEMBL3235972)
Affinity DataIC50: 548nMAssay Description:Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced Ca2+ influx incubated 2.5 mins prior to icilin chall...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed