BDBM50009835 4-Hydroxy-5-oxo-1-pyridin-4-ylmethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL266773

SMILES CCOC(=O)C1CN(Cc2ccncc2)C(=O)C1=O

InChI Key InChIKey=GOEUHBJSLVMWJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009835   

TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009835(CHEMBL266773 | 4-Hydroxy-5-oxo-1-pyridin-4-ylmethy...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of human placental aldose reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009835(CHEMBL266773 | 4-Hydroxy-5-oxo-1-pyridin-4-ylmethy...)
Affinity DataIC50: 110nMAssay Description:Percent inhibition of sorbitol accumulation in rat lens was measuredMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed