BDBM50010037 CHEMBL79598::N-Naphthalen-1-yl-N-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-methanesulfonamide

SMILES CS(=O)(=O)N(CCCN1CCC(=CC1)c1ccccc1)c1cccc2ccccc12

InChI Key InChIKey=SCPNMTOXHVHEIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010037   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010037(CHEMBL79598 | N-Naphthalen-1-yl-N-[3-(4-phenyl-3,6...)
Affinity DataIC50: 5.10nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010037(CHEMBL79598 | N-Naphthalen-1-yl-N-[3-(4-phenyl-3,6...)
Affinity DataIC50: 75nMAssay Description:The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010037(CHEMBL79598 | N-Naphthalen-1-yl-N-[3-(4-phenyl-3,6...)
Affinity DataIC50: 275nMAssay Description:The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed