BDBM50010052 2-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL440134

SMILES O=S1(=O)N(CCCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23

InChI Key InChIKey=OKJRBFNMYSRTKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010052   

TargetSerotonin 2 (5-HT2) receptor(Rat)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010052(CHEMBL440134 | 2-[4-(4-Phenyl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 2.10nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010052(CHEMBL440134 | 2-[4-(4-Phenyl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 7.80nMAssay Description:The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010052(CHEMBL440134 | 2-[4-(4-Phenyl-3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 55nMAssay Description:The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed