BDBM50010755 CHEMBL280243::N,N'-Bis-(2-isopropyl-phenyl)-guanidine

SMILES CC(C)c1ccccc1NC(N)=Nc1ccccc1C(C)C

InChI Key InChIKey=KCNBAUKGODRNGM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010755   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Oregon

Curated by ChEMBL
LigandPNGBDBM50010755(CHEMBL280243 | N,N'-Bis-(2-isopropyl-phenyl)-guani...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibitory activity against [3H]-DTG in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Oregon

Curated by ChEMBL
LigandPNGBDBM50010755(CHEMBL280243 | N,N'-Bis-(2-isopropyl-phenyl)-guani...)
Affinity DataIC50: 88nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed