BDBM50010845 CHEMBL581498::TCMDC-138893

SMILES CCCN(CCC)C(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNCc1cccc(OC)c1)N1CCCCS1(=O)=O

InChI Key InChIKey=OJKFYYWZUWDHRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010845   

TargetCathepsin D(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50010845(CHEMBL581498 | TCMDC-138893)
Affinity DataIC50: 360nMAssay Description:Inhibition of human cathepsin-D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50010845(CHEMBL581498 | TCMDC-138893)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins by FRET ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50010845(CHEMBL581498 | TCMDC-138893)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins by FRET ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed