BDBM50011216 1-Methyl-8-(1-methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::CHEMBL337073

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)Cc1ccccc1

InChI Key InChIKey=MFDOIDPESZOBLK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50011216   

TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50011216(CHEMBL337073 | 1-Methyl-8-(1-methyl-2-phenyl-ethyl...)
Affinity DataKi:  32.6nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50011216(CHEMBL337073 | 1-Methyl-8-(1-methyl-2-phenyl-ethyl...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50011216(CHEMBL337073 | 1-Methyl-8-(1-methyl-2-phenyl-ethyl...)
Affinity DataKi:  260nMAssay Description:Binding affinity carried out with [3H]cyclohexyladenosine in guinea pig forebrain membranes against adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50011216(CHEMBL337073 | 1-Methyl-8-(1-methyl-2-phenyl-ethyl...)
Affinity DataKi:  480nMAssay Description:Binding affinity carried out with [3H]5'-(N-ethylcarbamoyl)-adenosine in the presence of 50 nM cyclopentyladenosine in rat striatal membranes against...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50011216(CHEMBL337073 | 1-Methyl-8-(1-methyl-2-phenyl-ethyl...)
Affinity DataKi:  644nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed