BDBM50011235 CHEMBL3260333

SMILES CCn1ccc(Nc2ncc3n(nnc3n2)-c2ccc(cc2)C(C)(C)OCCO)n1

InChI Key InChIKey=XNAMZBCMLZQBIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011235   

TargeteIF-2-alpha kinase GCN2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50011235(CHEMBL3260333)
Affinity DataIC50: 300nMAssay Description:Inhibition of GCN2 (unknown origin) using GFP-elF2a as substrate preincubated with substrate for 20 mins measured after 90 mins by Lanthascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50011235(CHEMBL3260333)
Affinity DataIC50: 300nMAssay Description:Inhibition of GCN2-mediated elF2alpha phosphorylation in human U2OS cells after 2 hrs by immunocytochemistryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed