BDBM50011238 CHEMBL3260335::US9981909, Example 29

SMILES Cc1nc(COc2ccc(Cl)cc2OC2CNC2)cs1

InChI Key InChIKey=TXDVKDSWNUNCCI-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50011238   

TargetSodium-dependent serotonin transporter(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  27nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  27nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 7(Rat)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  83nMAssay Description:Binding affinity to rat 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  83nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  225nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  225nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  529nMAssay Description:Binding affinity to human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  529nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011238(CHEMBL3260335 | US9981909, Example 29)
Affinity DataKi:  1.11E+3nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent