BDBM50011240 CHEMBL3260337::US9981909, Example 200

SMILES C[C@@H](Oc1ccc(cc1OC1CNC1)C(F)(F)F)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=PQHWHHSAKLPIFS-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50011240   

Target5-hydroxytryptamine receptor 7(Rat)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  31nMAssay Description:Binding affinity to rat 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  31nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  224nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  224nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  605nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  605nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to human 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  5.00E+3nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  7.57E+3nMAssay Description:Binding affinity to human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50011240(CHEMBL3260337 | US9981909, Example 200)
Affinity DataKi:  7.57E+3nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent