BDBM50011672 2-{3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-prop-2-ynyl}-6,7-dimethoxy-3,4-dihydro-2H-isoquinolin-1-one::CHEMBL20691

SMILES COc1cc2CCN(CC#Cc3cc4c(s3)-n3c(C)nnc3CN=C4c3ccccc3Cl)C(=O)c2cc1OC

InChI Key InChIKey=NMVBVXNQIZWNSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011672   

TargetPlatelet-activating factor receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50011672(CHEMBL20691 | 2-{3-[4-(2-Chloro-phenyl)-9-methyl-6...)
Affinity DataIC50: 25nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed