BDBM50011736 CHEMBL3262909

SMILES CNc1oc(nc1C#N)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=MTKMTALYHIOLPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011736   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011736(CHEMBL3262909)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011736(CHEMBL3262909)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human 5-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011736(CHEMBL3262909)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011736(CHEMBL3262909)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human epithelial 15-lipoxygenase-2 using arachidonic acid as substrate by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed