BDBM50012128 CHEMBL3264011

SMILES CC(C)CN(Cc1ccc(cc1)-c1ccc(CC(N)=O)cc1)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=RYOODXLRWUTRMB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012128   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50012128(CHEMBL3264011)
Affinity DataEC50:  1.20E+3nMAssay Description:Inverse agonist activity at an N-terminal 6xHis-GST-tag human RORc-LBD assessed as inhibition of recruitment of the SRC1 co-activator peptide after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50012128(CHEMBL3264011)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from human RORc-LBD after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed