BDBM50012240 6-({[4-(Indole-1-sulfonyl)-phenyl]-prop-2-ynyl-amino}-methyl)-2-methyl-3H-quinazolin-4-one::CHEMBL299928

SMILES Cc1nc2ccc(CN(CC#C)c3ccc(cc3)S(=O)(=O)n3ccc4ccccc34)cc2c(=O)[nH]1

InChI Key InChIKey=RZPDNDSSUGJDEO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012240   

TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012240(CHEMBL299928 | 6-({[4-(Indole-1-sulfonyl)-phenyl]-...)
Affinity DataKi:  69nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012240(CHEMBL299928 | 6-({[4-(Indole-1-sulfonyl)-phenyl]-...)
Affinity DataKi:  150nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed