BDBM50012242 2-Methyl-6-[(phenyl-prop-2-ynyl-amino)-methyl]-3H-quinazolin-4-one::CHEMBL57333

SMILES Cc1nc2ccc(CN(CC#C)c3ccccc3)cc2c(=O)[nH]1

InChI Key InChIKey=KXQYGIYJFYJKAE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012242   

TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012242(CHEMBL57333 | 2-Methyl-6-[(phenyl-prop-2-ynyl-amin...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012242(CHEMBL57333 | 2-Methyl-6-[(phenyl-prop-2-ynyl-amin...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed