BDBM50012243 2-Methyl-6-{[prop-2-ynyl-(3-trifluoromethyl-phenyl)-amino]-methyl}-3H-quinazolin-4-one::CHEMBL301423

SMILES Cc1nc2ccc(CN(CC#C)c3cccc(c3)C(F)(F)F)cc2c(=O)[nH]1

InChI Key InChIKey=QDHQRSGEHWQARM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012243   

TargetThymidylate synthase(Human)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012243(CHEMBL301423 | 2-Methyl-6-{[prop-2-ynyl-(3-trifluo...)
Affinity DataKi:  390nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012243(CHEMBL301423 | 2-Methyl-6-{[prop-2-ynyl-(3-trifluo...)
Affinity DataKi:  450nMAssay Description:Inhibition of Thymidylate synthase of Escherichia coli (Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed