BDBM50012380 Acetic acid 2-biphenyl-4-yl-5-phenyl-thiazol-4-yl ester::CHEMBL304147

SMILES CC(=O)Oc1nc(sc1-c1ccccc1)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=SKOZBBRNMHJIAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012380   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012380(CHEMBL304147 | Acetic acid 2-biphenyl-4-yl-5-pheny...)
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012380(CHEMBL304147 | Acetic acid 2-biphenyl-4-yl-5-pheny...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed