BDBM50012633 CHEMBL3261046

SMILES C[C@]1(CCSC(N)=N1)c1cc(NC(=O)c2cnc(cn2)-n2cccn2)ccc1F

InChI Key InChIKey=OUKRQXJSFMAZTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012633   

TargetBeta-secretase 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012633(CHEMBL3261046)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed