BDBM50012667 CHEMBL3261070

SMILES CC1(N=C(N)CO[C@@H]1F)c1cc(NC(=O)c2ccc(Cl)cn2)ccc1F

InChI Key InChIKey=HBJCZLYQYZGGRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012667   

TargetBeta-secretase 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50012667(CHEMBL3261070)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using APP swedish mutant as substrate containing (7-methoxycoumarin-4-yl) acetic acid/2,4-Dinitrophe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed