BDBM50012703 2-Benzo[1,3]dioxol-5-ylmethyl-naphthalen-1-ol::CHEMBL341270

SMILES Oc1c(Cc2ccc3OCOc3c2)ccc2ccccc12

InChI Key InChIKey=VMGZBBCKRLGYRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012703   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012703(CHEMBL341270 | 2-Benzo[1,3]dioxol-5-ylmethyl-napht...)
Affinity DataIC50: 40nMAssay Description:Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50012703(CHEMBL341270 | 2-Benzo[1,3]dioxol-5-ylmethyl-napht...)
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-lipoxygenase in Rattus norvegicus Rat basophil leukemia cells (RBL) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article