BDBM50012788 1-(4-Fluoro-phenyl)-3-(4-hydroxy-3,5-dimethyl-phenyl)-propenone::CHEMBL58929

SMILES Cc1cc(\C=C\C(=O)c2ccc(F)cc2)cc(C)c1O

InChI Key InChIKey=RGSIGQQHMBKCKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012788   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012788(CHEMBL58929 | 1-(4-Fluoro-phenyl)-3-(4-hydroxy-3,5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012788(CHEMBL58929 | 1-(4-Fluoro-phenyl)-3-(4-hydroxy-3,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50012788(CHEMBL58929 | 1-(4-Fluoro-phenyl)-3-(4-hydroxy-3,5...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of NLRP3 in mouse J774A.1 cells infected with FLA-ST assessed as inhibition of LPS- induced IL-1beta production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed