BDBM50012865 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-carboxylic acid (2,4-difluoro-phenyl)-amide::CHEMBL64435

SMILES Fc1ccc(NC(=O)C2C(=O)N3c4c2cccc4Cc2ccccc32)c(F)c1

InChI Key InChIKey=GJLDPGXQDWKZDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012865   

TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012865(CHEMBL64435 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-d...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50012865(CHEMBL64435 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-d...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed