BDBM50012878 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-de]acridine-2-carboxylic acid (5-methyl-isoxazol-3-yl)-amide::CHEMBL444828

SMILES Cc1cc(NC(=O)C2C(=O)N3c4c2cccc4Cc2ccccc32)no1

InChI Key InChIKey=IFGDTAQWFWNREQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012878   

LigandPNGBDBM50012878(CHEMBL444828 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012878(CHEMBL444828 | 1-Oxo-1,2-dihydro-6H-pyrrolo[3,2,1-...)
Affinity DataIC50: 6.40E+3nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed