BDBM50013182 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl]-amide::CHEMBL141365

SMILES Fc1ccccc1C1=NC(CNC(=O)c2cc3ccccc3[nH]2)CNc2ccccc12

InChI Key InChIKey=HGKIQPBLDGUPTC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013182   

LigandPNGBDBM50013182(CHEMBL141365 | 1H-Indole-2-carboxylic acid [5-(2-f...)
Affinity DataIC50: 8.60nMAssay Description:Evaluated for its concentration required for displacement of [3H]-Naloxone from opioid receptors in rat brain tissuesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013182(CHEMBL141365 | 1H-Indole-2-carboxylic acid [5-(2-f...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013182(CHEMBL141365 | 1H-Indole-2-carboxylic acid [5-(2-f...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed