BDBM50013190 CHEMBL342256::[1-{[5-(2-Fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-ylmethyl]-carbamoyl}-2-(1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester

SMILES CN1C(CNC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)CN=C(c2ccccc2F)c2ccccc12

InChI Key InChIKey=POQAFSKCCQVOAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013190   

TargetGastrin/cholecystokinin type B receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013190(CHEMBL342256 | [1-{[5-(2-Fluoro-phenyl)-1-methyl-2...)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissuesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50013190(CHEMBL342256 | [1-{[5-(2-Fluoro-phenyl)-1-methyl-2...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed