BDBM50013215 CHEMBL2375156::Sodium salt of7-[4-(4-Fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid

SMILES Cc2c(/C=C/[C@H](O)C[C@@H](O)CC(=O)[O-])c(c1ccc(F)cc1)cn2c3ccccc3

InChI Key InChIKey=FQMQFMROIGKGDU-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013215   

LigandPNGBDBM50013215(CHEMBL2375156 | Sodium salt of7-[4-(4-Fluoro-pheny...)
Affinity DataIC50: 65nMAssay Description:Inhibition of cellular HMG-CoA reductase in cultures of hepatic cells (HEP G2, a human hepatoma cell line)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50013215(CHEMBL2375156 | Sodium salt of7-[4-(4-Fluoro-pheny...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed