BDBM50013627 22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl)

SMILES Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1

InChI Key InChIKey=XZBLPOKMIVGXML-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50013627   

TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013627(22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013627(22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013627(22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  28nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013627(22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  28nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013627(22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  746nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50013627(22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,...)
Affinity DataKi:  746nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed