BDBM50013845 CHEMBL3265290

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1cc(SCC(O)=O)c(O)c2ccccc12

InChI Key InChIKey=OPOQSWDNJPCXKP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013845   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013845(CHEMBL3265290)
Affinity DataIC50: 8.73E+3nMAssay Description:Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013845(CHEMBL3265290)
Affinity DataKi:  810nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed