BDBM50013848 8-[1-(4-Chloro-phenyl)-ethyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL312281

SMILES CC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=KFEYPBZJPJJRFX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013848   

TargetMu-type opioid receptor(Rat)
Louis Pasteur University

Curated by ChEMBL
LigandPNGBDBM50013848(CHEMBL312281 | 8-[1-(4-Chloro-phenyl)-ethyl]-1-phe...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50013848(CHEMBL312281 | 8-[1-(4-Chloro-phenyl)-ethyl]-1-phe...)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Louis Pasteur University

Curated by ChEMBL
LigandPNGBDBM50013848(CHEMBL312281 | 8-[1-(4-Chloro-phenyl)-ethyl]-1-phe...)
Affinity DataKi:  75nMAssay Description:Opioid receptor kappa 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed