BDBM50013858 CHEMBL3265291

SMILES OC(=O)CSc1cc(NS(=O)(=O)c2cccc(Br)c2)c2ccccc2c1O

InChI Key InChIKey=QRNTXTIRONJKOT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013858   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013858(CHEMBL3265291)
Affinity DataIC50: 9.68E+3nMAssay Description:Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013858(CHEMBL3265291)
Affinity DataKi:  180nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013858(CHEMBL3265291)
Affinity DataKi:  2.35E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed