BDBM50013890 CHEMBL3265288

SMILES Cc1cs\c(=N/C2CCCCC2)n1\N=C\c1ccc(O)c(O)c1O

InChI Key InChIKey=RGGFUBMUOVFZEF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50013890   

TargetBcl-2-like protein 1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013890(CHEMBL3265288)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLX-L (1 to 209) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013890(CHEMBL3265288)
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of FITC-labeled MCL1 (unknown origin) after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013890(CHEMBL3265288)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant FITC tagged MCL1 SAHBA binding to MCL1 deltaNdeltaC (unknown origin) expressed in Escherichia coli BL21 (DE3) by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013890(CHEMBL3265288)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Mcl-1 (unknown origin) measured after 5 mins by spectramax M5 microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50013890(CHEMBL3265288)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of FITC-MCL-1 SAHBa binding to recombinant MCL-1 (172 - 327 residues) (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed