BDBM50014107 (-)-(4-Methoxy-phenyl)-carbamic acid 1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indol-5-yl ester::1,3alpha,8-trimethyl-1,2,3,3alpha,8,8alpha-hexahydropyrrolo[2,3-b]indol-5-yl-4-methoxypheylcarbamate::CHEMBL74950

SMILES COc1ccc(NC(=O)Oc2ccc3N(C)[C@H]4N(C)CC[C@@]4(C)c3c2)cc1

InChI Key InChIKey=FYXWOKCKADGGGY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50014107   

TargetAcetylcholinesterase(Electric eel)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against Acetylcholinesterase in electric eelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against Acetylcholinesterase in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against Butyrylcholinesterase in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 29.9nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of rat plasma BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition acetylcholinesterase (AChE) enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against Acetylcholinesterase in erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50014107(CHEMBL74950 | 1,3alpha,8-trimethyl-1,2,3,3alpha,8,...)
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against Butyrylcholinesterase in plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed