BDBM50014151 ((1S,2R,3R,4S)-1-Benzyl-4-tert-butoxycarbonylamino-2,3-dihydroxy-5-phenyl-pentyl)-carbamic acid tert-butyl ester::CHEMBL9618::di-tert-butyl ((2S,3R,4R,5S)-3,4-dihydroxy-1,6-diphenylhexane-2,5-diyl)dicarbamate

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=XEFORNHNQOHGSE-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50014151   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014151(CHEMBL9618 | di-tert-butyl ((2S,3R,4R,5S)-3,4-dihy...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against recombinant HIV-1 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014151(CHEMBL9618 | di-tert-butyl ((2S,3R,4R,5S)-3,4-dihy...)
Affinity DataIC50: 280nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014151(CHEMBL9618 | di-tert-butyl ((2S,3R,4R,5S)-3,4-dihy...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014151(CHEMBL9618 | di-tert-butyl ((2S,3R,4R,5S)-3,4-dihy...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014151(CHEMBL9618 | di-tert-butyl ((2S,3R,4R,5S)-3,4-dihy...)
Affinity DataKi:  40nMAssay Description:Binding affinity to HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2014
Entry Details Article
PubMed