BDBM50014250 1-Benzyl-4-propyl-1,4,6,7-tetrahydro-imidazo[4,5-e][1,4]diazepine-5,8-dione::CHEMBL328776

SMILES CCCN1c2ncn(Cc3ccccc3)c2C(=O)NCC1=O

InChI Key InChIKey=HRXNTRRRYUYWIX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014250   

TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50014250(CHEMBL328776 | 1-Benzyl-4-propyl-1,4,6,7-tetrahydr...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity for Adenosine A1 receptor from rat brain using [3H]-PIA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50014250(CHEMBL328776 | 1-Benzyl-4-propyl-1,4,6,7-tetrahydr...)
Affinity DataKi:  1.63E+5nMAssay Description:Antagonism of N-ethylcarboxamido adenosine-stimulated adenylate cyclase associated with stimulation of Adenosine A2 receptor of rat PC12 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50014250(CHEMBL328776 | 1-Benzyl-4-propyl-1,4,6,7-tetrahydr...)
Affinity DataKi:  1.51E+5nMAssay Description:Binding affinity for Adenosine A2 receptor from rat striatum using [3H]NECA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed