BDBM50014593 CHEMBL3261750

SMILES CC(C)C[C@H](N)C(=O)NCC(=O)N[C@H]1C[C@H](N(C1)S(=O)(=O)c1ccc(C)cc1)C(=O)NO

InChI Key InChIKey=KDIOKKGMFBYKCS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014593   

Target72 kDa type IV collagenase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014593(CHEMBL3261750)
Affinity DataIC50: 870nMAssay Description:Inhibition of MMP2 (unknown origin) using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014593(CHEMBL3261750)
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of MMP2 in human SKOV3 cell suspension using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50014593(CHEMBL3261750)
Affinity DataIC50: 7.58E+4nMAssay Description:Inhibition of pig kidney microsomal APN using L-Leu-p-nitroanilide as substrate preincubated for 5 mins before substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed