BDBM50014843 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propyl]-formyl-amino}-benzoylamino)-pentanedioic acid::CHEMBL152172

SMILES Nc1nc(N)c(CCCN(C=O)c2ccc(cc2)C(=O)NC(CCC(O)=O)C(O)=O)c(=O)[nH]1

InChI Key InChIKey=KOOBXXUWGKUQCV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50014843   

TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase (GAR-TFase) against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase (GAR-TFase) against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 5.74E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed