BDBM50015418 CHEMBL3264641

SMILES CCCCn1cc(C(=O)Nc2ccc(C)c(c2)S(=O)(=O)N2CCOCC2)c(n1)-c1ccc(C)cc1

InChI Key InChIKey=ZVODXZMLMYFNDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015418   

TargetBile acid receptor(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015418(CHEMBL3264641)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at human GST-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50015418(CHEMBL3264641)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of GW4064-induced transactivation of FXR (unknown origin) expressed in HEK293T cells after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed