BDBM50015479 CHEMBL3265008

SMILES COc1ccc(Nc2nc(cn3ccnc23)-c2ccc(F)c(c2)C(N)=O)cc1OC

InChI Key InChIKey=MIASYBOTPYONAA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015479   

TargetTyrosine-protein kinase SYK(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015479(CHEMBL3265008)
Affinity DataEC50:  248nMAssay Description:Inhibition of Syk in antihuman IgM-stimulated human Ramos cells assessed as decrease in BCR-mediated BLNK phosphorylation by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015479(CHEMBL3265008)
Affinity DataIC50: 67nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed