BDBM50015681 CHEMBL3260593

SMILES Cc1cccc(n1)-c1[nH]c(CNc2cccc(CC#N)c2)nc1-c1ccc2ncnn2c1

InChI Key InChIKey=ZHNIIDZRMBVNFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015681   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50015681(CHEMBL3260593)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as substrate by radioisotopic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50015681(CHEMBL3260593)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as substrate by radioisotopic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed