BDBM50015696 6-{[(4-Acetyl-phenyl)-prop-2-ynyl-amino]-methyl}-3H-quinazolin-4-one::CHEMBL64215

SMILES CC(=O)c1ccc(cc1)N(CC#C)Cc1ccc2nc[nH]c(=O)c2c1

InChI Key InChIKey=HIXJSMKXJILFDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015696   

TargetThymidylate synthase(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015696(CHEMBL64215 | 6-{[(4-Acetyl-phenyl)-prop-2-ynyl-am...)
Affinity DataIC50: 2.40E+3nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015696(CHEMBL64215 | 6-{[(4-Acetyl-phenyl)-prop-2-ynyl-am...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed