BDBM50015701 6-{[(4-Acetyl-phenyl)-prop-2-ynyl-amino]-methyl}-2-amino-3H-quinazolin-4-one::CHEMBL62599

SMILES CC(=O)c1ccc(cc1)N(CC#C)Cc1ccc2nc(N)[nH]c(=O)c2c1

InChI Key InChIKey=KWSUUWFDIXJBRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015701   

TargetThymidylate synthase(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015701(CHEMBL62599 | 6-{[(4-Acetyl-phenyl)-prop-2-ynyl-am...)
Affinity DataIC50: 770nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015701(CHEMBL62599 | 6-{[(4-Acetyl-phenyl)-prop-2-ynyl-am...)
Affinity DataIC50: 3.73E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed