BDBM50015708 2-Amino-6-{[(4-nitro-phenyl)-prop-2-ynyl-amino]-methyl}-3H-quinazolin-4-one::CHEMBL62769

SMILES Nc1nc2ccc(CN(CC#C)c3ccc(cc3)[N+]([O-])=O)cc2c(=O)[nH]1

InChI Key InChIKey=MNUZJESDLXCPRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015708   

TargetThymidylate synthase(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015708(CHEMBL62769 | 2-Amino-6-{[(4-nitro-phenyl)-prop-2-...)
Affinity DataIC50: 620nMAssay Description:The compound was not tested for inhibition of L1210 Thymidylate synthase due to insolubilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50015708(CHEMBL62769 | 2-Amino-6-{[(4-nitro-phenyl)-prop-2-...)
Affinity DataIC50: 2.26E+4nMAssay Description:Tested for 50% inhibition of WI-L2 Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed