BDBM50015825 CHEMBL73133::Methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl-amine

SMILES CNc1nc2ccccc2n2cnnc12

InChI Key InChIKey=OKMBFCGUSTURFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50015825   

TargetDNA topoisomerase 2-alpha(Human)
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50015825(CHEMBL73133 | Methyl-[1,2,4]triazolo[4,3-a]quinoxa...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015825(CHEMBL73133 | Methyl-[1,2,4]triazolo[4,3-a]quinoxa...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed