BDBM50016185 CHEMBL3262132

SMILES Cl.C(Oc1cccnc1)[C@H]1CNCCN1c1nc2ncccc2o1

InChI Key InChIKey=ZWCUBSOPHPGVRD-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016185   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016185(CHEMBL3262132)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016185(CHEMBL3262132)
Affinity DataIC50: 58nMAssay Description:Inhibition of human alpha4beta2 nAChR expressed in Xenopus oocytes by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016185(CHEMBL3262132)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus oocytes by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Critical Therapeutics

Curated by ChEMBL
LigandPNGBDBM50016185(CHEMBL3262132)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human ERG by whole-cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed